Table 2 The GRADE evidence quality
Outcome | Number of studies/patients | Effect | Limitations | Inconsistency | Indirectness | Imprecision | Quality |
|---|---|---|---|---|---|---|---|
Pain score in PACU | 3/272 | WMD = −0.598, 95% CI [− 0.886, −0.310] | No serious limitations | No serious inconsistency | No serious indirectness | No serious limitations | High |
Pain score at 6 h | 3/272 | WMD = −0.614, 95% CI [− 0.835, −0.392] | No serious limitations | No serious inconsistency | No serious indirectness | No serious limitations | High |
Pain score at 24 h | 4/744 | WMD = −0.924, 95% CI [− 1.929, 0.081] | No serious limitations | Serious inconsistency | No serious indirectness | Serious limitations | Low |
Pain score at 48 h | 4/744 | WMD = −0.533, 95% CI [− 1.055, −0.012] | No serious limitations | Serious inconsistency | No serious indirectness | Serious limitations | Low |
Time to first opioid | 3/626 | WMD = 5.214, 95% CI [4.545, 5.883] | No serious limitations | No serious inconsistency | No serious indirectness | No serious limitations | High |
Opioid consumption at 24 h | 3/678 | WMD = − 6.168, 95% CI [− 6.667, − 5.668] | No serious limitations | No serious inconsistency | No serious indirectness | No serious limitations | High |
Opioid consumption at 48 h | 5/808 | WMD = − 7.171, 95% CI [− 8.994, − 5.348] | No serious limitations | Serious inconsistency | No serious indirectness | No serious limitations | Moderate |
Incidence of complications | 3/220 | OR = 0.840, 95% CI [0.528, 1.336] | No serious limitations | No serious inconsistency | No serious indirectness | No serious limitations | High |