Fig. 2
![Fig. 2](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs13018-023-04494-x/MediaObjects/13018_2023_4494_Fig2_HTML.png)
Circ_HECW2 was highly expressed in LPS-induced osteoblasts. Human osteoblasts HFOB1.19 were treated with 10 µg/mL LPS for 24 h, with cells free of LPS treatment as the control. A RT-qPCR detected Circ_HECW2 expression in cells. B TUNEL detected cell apoptosis. C Western blot detected the apoptosis related protein cleaved-caspase-3. The cell experiments were independently repeated 3 times. Data were expressed as mean ± standard deviation and analyzed using t test, *P < 0.05